SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                  SCHEDULE 13G

                                 (RULE 13d-102)

   Information to be Included in Statements Filed Pursuant to ss.240.13d-1(b),
        (c) and (d) and Amendments Thereto Filed Pursuant to ss.240.13d-2

                    Under the Securities Exchange Act of 1934

                               (Amendment No. 3)*


                            Keryx Biopharmaceuticals
                         ------------------------------
                                (Name of Issuer)

                                  Common Stock
                         ------------------------------
                         (Title of Class of Securities)

                                    492515101
                         ------------------------------
                                 (CUSIP Number)

                                December 31, 2008
             -------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

       Check the appropriate box to designate the rule pursuant to which
                             this Schedule is filed:

                                (x) Rule 13d-1(b)
                                ( ) Rule 13d-1(c)
                                ( ) Rule 13d-1(d)

----------------
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                        (Continued on following page(s))






1.   NAME OF REPORTING PERSONS

     TIAA-CREF Investment Management, LLC

2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)( )
                                                        (b)( )

3. SEC USE ONLY

4.   CITIZENSHIP OR PLACE OF ORGANIZATION

     Delaware

NUMBER OF SHARES BENEFICIALLY OWNED
BY EACH REPORTING PERSON WITH:

     5. SOLE VOTING POWER                    184,806

     6. SHARED VOTING POWER                  0

     7. SOLE DISPOSITIVE POWER               184,806

     8. SHARED DISPOSITIVE POWER             0

9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                                     184,806

10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ( )

11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                                     0.41 %

12.  TYPE OF REPORTING PERSON

                                     IA






1.   NAME OF REPORTING PERSONS

     College Retirement Equities Fund - Stock Account

2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)( )
                                                        (b)( )

3.   SEC USE ONLY

4.   CITIZENSHIP OR PLACE OF ORGANIZATION

     New York

NUMBER OF SHARES BENEFICIALLY OWNED
BY EACH REPORTING PERSON WITH:

     5. SOLE VOTING POWER                    0

     6. SHARED VOTING POWER                  0

     7. SOLE DISPOSITIVE POWER               0

     8. SHARED DISPOSITIVE POWER             0

9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                                     0

10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ( )

11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                                     0.00%

12.  TYPE OF REPORTING PERSON

                                     IV






1.   NAME OF REPORTING PERSONS

     Teachers Advisors, Inc.

2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)( )
                                                        (b)( )

3.   SEC USE ONLY

4.   CITIZENSHIP OR PLACE OF ORGANIZATION

     Delaware

NUMBER OF SHARES BENEFICIALLY OWNED
BY EACH REPORTING PERSON WITH:

     5. SOLE VOTING POWER                    0

     6. SHARED VOTING POWER                  0

     7. SOLE DISPOSITIVE POWER               0

     8. SHARED DISPOSITIVE POWER             0

9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                                     0

10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ( )

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                                     0.00%

12.  TYPE OF REPORTING PERSON

                                     IA






ITEM 1(a).    NAME OF ISSUER:

                      Keryx Biopharmaceuticals

ITEM 1(b).    ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

                      750 Lexington Avenue
                      New York, NY 10022

ITEMS 2(a)-2(c).      NAME, ADDRESS OF PRINCIPAL BUSINESS OFFICE, AND
                      CITIZENSHIP OF PERSONS FILING:

                      TIAA-CREF Investment Management, LLC
                      ("Investment Management")
                      730 Third Avenue
                      New York, NY 10017-3206
                      Citizenship:  Delaware

                      College Retirement Equities Fund-Stock Account
                      ("CREF Stock Account")
                      730 Third Avenue
                      New York, NY 10017-3206
                      Citizenship:  New York

                      Teachers Advisors, Inc. ("Advisors")
                      730 Third Avenue
                      New York, NY 10017-3206
                      Citizenship:  Delaware

ITEM 2(d).    TITLE OF CLASS OF SECURITIES:

                      Common Stock

ITEM 2(e).    CUSIP NUMBER:

                      492515101

ITEM 3.       IF THIS STATEMENT IS FILED PURSUANT TO SECTION 240.13d-1(b), OR
              SECTION 240.13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A:


INVESTMENT MANAGEMENT

(a)   ( )     Broker or dealer registered under Section 15 of the Exchange Act.

(b)   ( )     Bank as defined in Section 3(a)(6) of the Exchange Act.

(c)   ( )     Insurance Company as defined in Section 3(a)(19) of the Exchange
              Act.

(d)   ( )     Investment Company registered under Section 8 of the Investment
              Company Act.

(e)   (x)     An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).

(f)   ( )     An employee benefit plan or endowment fund in accordance with
              Rule 13d-1(b)(1)(ii)(F).

(g)   ( )     A parent holding company or control person in accordance with
              Rule 13d-1(b)(1)(ii)(G).

(h)   ( )     A savings association as defined in Section 3(b) of the Federal
              Deposit Insurance Act.

(i)   ( )     A church plan that is excluded from the definition of an






              investment company under Section 3(c)(14) of the Investment
              Company Act.

(j)   ( )     Group, in accordance with Rule 13d-1(b)(1)(ii)(J).


CREF STOCK ACCOUNT

(a)   ( )     Broker or dealer registered under Section 15 of the Exchange Act.

(b)   ( )     Bank as defined in Section 3(a)(6) of the Exchange Act.

(c)   ( )     Insurance Company as defined in Section 3(a)(19) of the Exchange
              Act.

(d)   (x)     Investment Company registered under Section 8 of the Investment
              Company Act.

(e)   ( )     An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).

(f)   ( )     An employee benefit plan or endowment fund in accordance with
              Rule 13d-1(b)(1)(ii)(F).

(g)   ( )     A parent holding company or control person in accordance with
              Rule 13d-1(b)(1)(ii)(G).

(h)   ( )     A savings association as defined in Section 3(b) of the Federal
              Deposit Insurance Act.

(i)   ( )     A church plan that is excluded from the definition of an
              investment company under Section 3(c)(14) of the Investment
              Company Act.

(j)   ( )     Group, in accordance with Rule 13d-1(b)(1)(ii)(J).


ADVISORS

(a)   ( )     Broker or dealer registered under Section 15 of the Exchange Act.

(b)   ( )     Bank as defined in Section 3(a)(6) of the Exchange Act.

(c)   ( )     Insurance Company as defined in Section 3(a)(19) of the Exchange
              Act.

(d)   ( )     Investment Company registered under Section 8 of the Investment
              Company Act.

(e)   (x)     An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).

(f)   ( )     An employee benefit plan or endowment fund in accordance with
              Rule 13d-1(b)(1)(ii)(F).

(g)   ( )     A parent holding company or control person in accordance with
              Rule 13d-1(b)(1)(ii)(G).

(h)   ( )     A savings association as defined in Section 3(b) of the Federal
              Deposit Insurance Act.

(i)   ( )     A church plan that is excluded from the definition of an
              investment company under Section 3(c)(14) of the Investment
              Company Act.

(j)   ( )     Group, in accordance with Rule 13d-1(b)(1)(ii)(J).


If this statement is filed pursuant to Rule 13d-1(c), check this box. ( )






ITEM 4.       OWNERSHIP

         Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1:

              (a) Aggregate amount beneficially owned: 184,806 (See Exhibit A)

              (b) Percent of class:                    0.41%

              (c) Number of shares as to which the person has:



                                INVESTMENT MANAGEMENT     CREF- STOCK ACCOUNT      ADVISORS
                                                                          
Sole Voting Power:              184,806                   0                        0

Shared Voting Power:            0                         0                        0

Sole Dispositive Power:         184,806                   0                        0

Shared Dispositive Power:       0                         0                        0


ITEM 5.       OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

              If this statement is being filed to report the fact that as of the
              date hereof the reporting person has ceased to be the beneficial
              owner of more than 5 percent of the class of securities, check the
              following (x). See Exhibit A.

ITEM 6.       OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

              Not Applicable

ITEM 7.       IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
              THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.

              Not Applicable

ITEM 8.       IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

              Not Applicable

ITEM 9.       NOTICE OF DISSOLUTION OF GROUP.

              Not Applicable






ITEM 10.      CERTIFICATIONS.

              By signing below I certify that, to the best of my knowledge and
              belief, the securities referred to above were acquired and are
              held in the ordinary course of business and were not acquired and
              are not held for the purpose of or with the effect of changing or
              influencing the control of the issuer of the securities and were
              not acquired and are not held in connection with or as a
              participant in any transaction having that purpose or effect.


              SIGNATURE.

              After reasonable inquiry and to the best of my knowledge and
              belief, I certify that the information set forth in this statement
              is true, complete and correct.

              Date: February 13, 2009

                                             TIAA-CREF INVESTMENT
                                             MANAGEMENT, LLC

                                             By: /s/ Michael Albert
                                                 ------------------
                                             Michael Albert
                                             Managing Director, Control Services


                                             COLLEGE RETIREMENT EQUITIES
                                             FUND-STOCK ACCOUNT

                                             By: /s/ Michael Albert
                                                 ------------------
                                             Michael Albert
                                             Managing Director Control Services


                                             TEACHERS ADVISORS, INC.

                                             By: /s/ Michael Albert
                                                 ------------------
                                             Michael Albert
                                             Managing Director, Control Services






                                    EXHIBIT A

ITEM 6.  OWNERSHIP.

TIAA-CREF Investment Management, LLC ("Investment Management") acts as the
investment adviser to the College Retirement Equities Fund ("CREF"), a
registered investment company, and may be deemed to be a beneficial owner of
184,806 shares of Issuer's common stock owned by CREF. The CREF Stock Account no
longer holds any shares of Issuer's common stock. Teachers Advisors, Inc.
("Advisors") is the investment adviser to two registered investment companies,
TIAA-CREF Funds ("Mutual Funds"), and TIAA Separate Account VA-1 ("VA-1"), as
well as the TIAA-CREF Asset Management Commingled Funds Trust I ("TCAM Funds"),
none of which now hold shares of Issuer's common stock. Investment Management
and Advisors are reporting their combined holdings for the purpose of
administrative convenience. These shares were acquired in the ordinary course of
business, and not with the purpose or effect of changing or influencing control
of the Issuer. Each of Investment Management and Advisors expressly disclaims
beneficial ownership of the other's securities holdings and each disclaims that
it is a member of a "group" with the other.