UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 ------------------------------------------------------------------------------ FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 15, 2003 ENZO BIOCHEM, INC. (Exact Name of Registrant as Specified in Charter) New York 001-09974 13-2866202 (State or Other Jurisdiction of (Commission File Number) (I.R.S. Employer Incorporation or Organization) Identification No.) 60 Executive Boulevard, Farmingdale, New York 11735 (Address of Principal Executive Offices) (Zip Code) Registrant's telephone number, including area code: (631) 755-5500 NOT APPLICABLE -------------- (Former name or former address, if changed since last report) ------------------------------------------------------------------------------ ITEM 12. RESULTS OF OPERATIONS AND FINANCIAL CONDITION. On December 15, 2003, the Registrant issued a press release announcing its operating results for the fiscal quarter ended October 31, 2003. A copy of the press release is furnished as Exhibit 99.1 to this Current Report. The information in this Current Report and the exhibits attached hereto are being "furnished" hereunder and shall not be deemed filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), nor shall they be deemed incorporated by reference into any filings made by the Registrant with the Securities and Exchange Commission under the Exchange Act or the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filings. 2 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Date: December 15, 2003 Enzo Biochem, Inc. By: /s/ Barry Weiner ----------------------------------- Name: Barry Weiner Title: Chief Financial Officer 3 EXHIBIT INDEX EXHIBIT DESCRIPTION ------- ----------- 99.1 Registrant's press release dated December 15, 2003 announcing operating results for the fiscal quarter ended October 31, 2003.* * Furnished herewith. 4