UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: December 31, 2005 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name:GENERAL AMERICAN INVESTORS COMPANY, INC. Address: 450 Lexington Ave, Suite 3300 New York, NY 10017 13F File Number: 28-461 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Eugene S. Stark Title: Vice-President, Administration Phone: 212-916-8447 Signature, Place, and Date of Signing: Eugene S. Stark New York, NY February 9, 2006 Report Type (Check only one.): [X] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ ] 13F COMBINATION REPORT. FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 57 Form 13F Information Table Value Total: $1287580900 List of Other Included Managers: NONE COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8 -------------- --------- --------- -------- ------------- -------- -------- ------------------ VALUE SHARES/ SH/ PUT/ INVSTMT OTHER -----VOTING AUTHORITY----- NAME OF ISSUER -TITLE OF CLASS- --CUSIP-- x$1000 PRN AMT PRN CALL DSCRETN -MANAGERS- SOLE SHARED NONE Arch Capital Group Ltd. COMMON G0450A105 19163 350000 SH SOLE 350000 0 0 Adams Express Company COMMON 006212104 1319 105075 SH SOLE 105075 0 0 American International Group,Inc COMMON 026874107 23539 345000 SH SOLE 345000 0 0 Alkermes, Inc. COMMON 01642T108 5067 265000 SH SOLE 265000 0 0 The Allstate Corporation COMMON 020002101 9192 170000 SH SOLE 170000 0 0 American Tower Corporation COMMON 029912201 18293 675000 SH SOLE 675000 0 0 Annuity and Life Re (Holdings), COMMON G03910109 575 500000 SH SOLE 500000 0 0 Apache Corporation COMMON 037411105 45566 665000 SH SOLE 665000 0 0 Bank of America Corporation COMMON 060505104 12922 280000 SH SOLE 280000 0 0 Bed Bath & Beyond Inc. COMMON 075896100 7230 200000 SH SOLE 200000 0 0 Bancroft Convertible Fund COMMON 059695106 386 21374 SH SOLE 21374 0 0 Biogen Idec Inc. COMMON 09062X103 8150 180000 SH SOLE 180000 0 0 Berkshire Hathaway Inc. Class A COMMON 084670108 26586 300 SH SOLE 300 0 0 Brooks Automation, Inc. COMMON 114340102 4047 323000 SH SOLE 323000 0 0 Central Securities Corporation COMMON 155123102 620 26055 SH SOLE 26055 0 0 Costco Wholesale Corporation COMMON 22160K105 34629 700000 SH SOLE 700000 0 0 Cisco Systems, Inc. COMMON 17275R102 15408 900000 SH SOLE 900000 0 0 CEMEX, S.A. de C.V. ADR COMMON 151290889 67817 1143041 SH SOLE 1143041 0 0 Cytokinetics, Incorporated COMMON 23282W100 3956 604900 SH SOLE 604900 0 0 Diageo plc COMMON 25243Q205 20405 350000 SH SOLE 350000 0 0 Dollar General Corporation COMMON 256669102 14303 750000 SH SOLE 750000 0 0 Genentech, Inc. COMMON 368710406 30525 330000 SH SOLE 330000 0 0 Devon Energy Corporation COMMON 25179M103 47405 758000 SH SOLE 758000 0 0 EMC Corporation COMMON 268648102 4086 300000 SH SOLE 300000 0 0 EMCORE Corporation COMMON 290846104 1462 197000 SH SOLE 197000 0 0 EOG Resources, Inc. COMMON 26875P101 44022 600000 SH SOLE 600000 0 0 Ethan Allen Interiors Inc. COMMON 297602104 10046 275000 SH SOLE 275000 0 0 Golden West Financial COMMON 381317106 38610 585000 SH SOLE 585000 0 0 Halliburton Company COMMON 406216101 27262 440000 SH SOLE 440000 0 0 The Home Depot, Inc. COMMON 437076102 68614 1695000 SH SOLE 1695000 0 0 Lafarge North America Inc. COMMON 505862102 9629 175000 SH SOLE 175000 0 0 Lamar Advertising Company COMMON 512815101 16146 350000 SH SOLE 350000 0 0 Medtronic, Inc. COMMON 585055106 25907 450000 SH SOLE 450000 0 0 MedImmune, Inc. COMMON 584699102 14008 400000 SH SOLE 400000 0 0 MetLife, Inc. COMMON 59156R108 13965 285000 SH SOLE 285000 0 0 MFA Mortgage Investments, Inc. COMMON 55272X102 7410 1300000 SH SOLE 1300000 0 0 Molex Incorporated Class A COMMON 608554200 13525 550000 SH SOLE 550000 0 0 Microsoft Corporation COMMON 594918104 36610 1400000 SH SOLE 1400000 0 0 M&T Bank Corporation COMMON 55261F104 33806 310000 SH SOLE 310000 0 0 North Fork Bancorporation, Inc. COMMON 659424105 16416 600000 SH SOLE 600000 0 0 Annaly Mortgage Management, Inc. COMMON 035710409 5470 500000 SH SOLE 500000 0 0 PepsiCo, Inc. COMMON 713448108 10339 175000 SH SOLE 175000 0 0 Pfizer Inc COMMON 717081103 29150 1250000 SH SOLE 1250000 0 0 PartnerRe Ltd. COMMON G6852T105 24626 375000 SH SOLE 375000 0 0 Patterson-UTI Energy, Inc. COMMON 703481101 32950 1000000 SH SOLE 1000000 0 0 Everest Re Group, Ltd. COMMON G3223R108 54189 540000 SH SOLE 540000 0 0 Republic Services, Inc. COMMON 760759100 44121 1175000 SH SOLE 1175000 0 0 Royce Value Trust COMMON 780910105 2261 112611 SH SOLE 112611 0 0 SunTrust Banks, Inc. COMMON 867914103 14552 200000 SH SOLE 200000 0 0 The TJX Companies, Inc. COMMON 872540109 58075 2500000 SH SOLE 2500000 0 0 Talisman Energy Inc. COMMON 87425E103 52880 1000000 SH SOLE 1000000 0 0 Total S.A. ADR COMMON 89151E109 41712 330000 SH SOLE 330000 0 0 Transatlantic Holdings, Inc. COMMON 893521104 16800 250000 SH SOLE 250000 0 0 VeriSign, Inc. COMMON 92343E102 2924 133500 SH SOLE 133500 0 0 Weatherford International Ltd. COMMON G95089101 44164 1220000 SH SOLE 1220000 0 0 Wal-Mart Stores, Inc. COMMON 931142103 26910 575000 SH SOLE 575000 0 0 Xerox Corporation COMMON 984121103 27835 1900000 SH SOLE 1900000 0 0