Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
AKKARAJU SRINIVAS
  2. Issuer Name and Ticker or Trading Symbol
SEATTLE GENETICS INC /WA [SGEN]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
21823 30TH DRIVE SE
3. Date of Earliest Transaction (Month/Day/Year)
06/21/2010
(Street)

BOTHELL, WA 98021
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/21/2010   M(1)   10,000 A $ 7.26 20,405 (2) D  
Common Stock 06/21/2010   J(2)   10,000 D $ 0 10,405 (2) D  
Common Stock 06/21/2010   M(1)   10,000 A $ 5.11 20,405 (2) D  
Common Stock 06/21/2010   J(2)   10,000 D $ 0 10,405 (2) D  
Common Stock 06/21/2010   M(1)   10,000 A $ 4.18 20,405 (2) D  
Common Stock 06/21/2010   J(2)   10,000 D $ 0 10,405 (2) D  
Common Stock 06/21/2010   M(1)   10,000 A $ 10.2 20,405 (2) D  
Common Stock 06/21/2010   J(2)   10,000 D $ 0 10,405 (2) D  
Common Stock 06/21/2010   M(1)   10,000 A $ 10.08 20,405 (2) D  
Common Stock 06/21/2010   J(2)   10,000 D $ 0 10,405 (2) D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 4.18 06/21/2010   M(1)     10,000   (3) 05/19/2016 Common Stock 10,000 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 5.11 06/21/2010   M(1)     10,000   (4) 05/13/2015 Common Stock 10,000 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 7.26 06/21/2010   M(1)     10,000   (5) 05/17/2014 Common Stock 10,000 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 10.08 06/21/2010   M(1)     10,000   (6) 05/16/2018 Common Stock 10,000 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 10.2 06/21/2010   M(1)     10,000   (7) 05/25/2017 Common Stock 10,000 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
AKKARAJU SRINIVAS
21823 30TH DRIVE SE
BOTHELL, WA 98021
  X      

Signatures

 /s/ Eric L. Dobmeier For: Srinivas Akkaraju   06/23/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This option was granted to Srinivas Akkaraju, a director of the Issuer. Dr. Akkaraju was contractually obligated to exercise this option at the discretion of J.P. Morgan Partners (BHCA), L.P. ("JPM BHCA"), which was contractually entitled to the shares issued upon exercise of the option. JPM BHCA may be deemed to be indirect beneficial owner of the option. Dr. Akkaraju disclaims beneficial ownership of this option and the shares issued upon exercise thereof, and this report shall not be deemed an admission that Dr. Akkaraju is or was the beneficial owner of such securities for purposes of Section 16 of the Exchange Act of 1934, as amended (the "Exchange Act"), or for any other purpose.
(2) See Footnote (1). All of the shares acquired upon exercise of each option (the "Exercise Shares") were transferred to JPM BHCA pursuant to Dr. Akkaraju's contractual obligation. Dr. Akkaraju disclaims beneficial ownership of the Exercise Shares and this report shall not be deemed an admission that Dr. Akkaraju is or was the beneficial owner of the Exercise Shares for purposes of Section 16 of the Exchange Act or for any other purpose.
(3) The option vested in full on May 18, 2007.
(4) The option vested in full on May 12, 2006.
(5) The options vested in full May 16, 2005.
(6) The option vested in full on May 15, 2009.
(7) The option vested in full on May 24, 2008.

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