Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  O'Donnell Mark Sean
 2. Date of Event Requiring Statement (Month/Day/Year)
11/21/2008		 3. Issuer Name and Ticker or Trading Symbol
Life Technologies Corp [LIFE]
(Last)
(First)
(Middle)
5791 VAN ALLEN WAY		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
SVP, Global Ops & Services
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

CARLSBAD, CA 92008		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Incentive Stock Option (1) (10) 11/21/2008 03/17/2010 Common Stock 1,572 $ 115.51 D  
Non-Qualified Stock Option (2) 11/21/2008 03/17/2010 Common Stock 9,995 $ 115.51 D  
Non-Qualified Stock Option (3) 11/21/2008 03/24/2013 Common Stock 4,349 $ 17.87 D  
Non-Qualified Stock Option (4) 11/21/2008 06/17/2014 Common Stock 8,480 $ 23.21 D  
Non-Qualified Stock Option (5) 11/21/2008 06/02/2015 Common Stock 5,436 $ 24.69 D  
Non-Qualified Stock Option (6) 11/21/2008 06/02/2015 Common Stock 5,436 $ 24.69 D  
Non-Qualified Stock Option (7) 11/21/2008 06/02/2015 Common Stock 5,436 $ 24.69 D  
Non-Qualified Stock Option (8) 11/21/2008 06/02/2015 Common Stock 5,436 $ 24.69 D  
Non-Qualified Stock Option (9) 11/21/2008 01/30/2017 Common Stock 19,135 $ 39.81 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
O'Donnell Mark Sean
5791 VAN ALLEN WAY
CARLSBAD, CA 92008		       SVP, Global Ops & Services  

Signatures

/s/ Joseph W. Secondine, Jr. POA 11/25/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Incentive Stock Option grant # 00005377. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(2) Non-Qualified Stock Option grant # 00085378. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(3) Non-Qualified Stock Option grant # 00017222. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(4) Non-Qualified Stock Option grant # 00021103. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(5) Non-Qualified Stock Option grant # 00020503. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(6) Non-Qualified Stock Option grant # A0020503. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(7) Non-Qualified Stock Option grant # B0020503. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(8) Non-Qualified Stock Option grant # C0020503. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(9) Non-Qualified Stock Option grant # 18801. Shares converted to LIFE as a result of the Applied Biosystems merger with Invitrogen Corporation (name subsequently changed to Life Technologies).
(10) The individual may hold additional shares acquired as a result of the conversion from Applied Biosystems stock to Life Technologies stock. Administration of the conversion is not complete. If it is determined that the individual owns shares, a Form 4A will be filed.

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