Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
SHARER KEVIN W
   2. Issuer Name and Ticker or Trading Symbol
AMGEN INC [AMGN] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chairman of the Bd, CEO & Pres
(Last)
(First)
(Middle)
ONE AMGEN CENTER DRIVE		 3. Date of Earliest Transaction (Month/Day/Year)
07/28/2005
(Street)

THOUSAND OAKS, CA 91320-1799		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 07/28/2005   S   2,300 D $ 81.0339 151,801 D  
Common Stock 07/28/2005   S   1,000 D $ 81.034 150,801 D  
Common Stock 07/28/2005   S   1,470 D $ 81.035 149,331 D  
Common Stock 07/28/2005   S   1,800 D $ 81.0367 147,531 D  
Common Stock 07/28/2005   S   675 D $ 81.04 146,856 D  
Common Stock 07/28/2005   S   4,028 D $ 81.0429 142,828 D  
Common Stock 07/28/2005   S   1,955 D $ 81.0431 140,873 D  
Common Stock 07/28/2005   S   3,121 D $ 81.0465 137,752 D  
Common Stock 07/28/2005   S   1,412 D $ 81.0479 136,340 D  
Common Stock 07/28/2005   S   2,099 D $ 81.049 134,241 D  
Common Stock 07/28/2005   S   3,170 D $ 81.0498 131,071 D  
Common Stock 07/28/2005   S   2,165 D $ 81.05 128,906 D  
Common Stock 07/28/2005   S   1,548 D $ 81.0513 127,358 D  
Common Stock 07/28/2005   S   1,300 D $ 81.0538 126,058 D  
Common Stock 07/28/2005   S   1,100 D $ 81.0564 124,958 D  
Common Stock 07/28/2005   S   1,122 D $ 81.0573 123,836 D  
Common Stock 07/28/2005   S   1,200 D $ 81.0575 122,636 D  
Common Stock 07/28/2005   S   2,192 D $ 81.06 120,444 D  
Common Stock 07/28/2005   S   1,400 D $ 81.0607 119,044 D  
Common Stock 07/28/2005   S   1,350 D $ 81.0611 117,694 D  
Common Stock 07/28/2005   S   1,795 D $ 81.0617 115,899 D  
Common Stock 07/28/2005   S   3,600 D $ 81.0625 112,299 D  
Common Stock 07/28/2005   S   900 D $ 81.0633 111,399 D  
Common Stock 07/28/2005   S   1,481 D $ 81.0649 109,918 D  
Common Stock 07/28/2005   S   900 D $ 81.0656 109,018 D  
Common Stock 07/28/2005   S   1,838 D $ 81.0693 107,180 D  
Common Stock 07/28/2005   S   3,438 D $ 81.0697 103,742 D  
Common Stock 07/28/2005   S   1,082 D $ 81.07 102,660 D  
Common Stock 07/28/2005   S   1,800 D $ 81.0717 100,860 D  
Common Stock 07/28/2005   S   2,700 D $ 81.0741 98,160 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
SHARER KEVIN W
ONE AMGEN CENTER DRIVE
THOUSAND OAKS, CA 91320-1799		   X     Chairman of the Bd, CEO & Pres  

Signatures

 /s/ Kevin W Sharer N. Cris Prince By Power of Attorney   08/01/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

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