FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * DENNY JAMES M   2. Issuer Name and Ticker or Trading Symbol GILEAD SCIENCES INC [GILD] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 333 LAKESIDE DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 03/06/2007 (Street) FOSTER CITY, CA 94404 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/06/2007   M   10,000 A $ 5.1329 69,600 D   Common Stock 03/06/2007   M   13,600 A $ 5.1329 83,200 D   Common Stock 03/06/2007   M   16,400 A $ 6.7657 99,600 D   Common Stock 03/06/2007   S   101 D $ 70.35 99,499 D   Common Stock 03/06/2007   S   15 D $ 70.4 99,484 D   Common Stock 03/06/2007   S   400 D $ 70.42 99,084 D   Common Stock 03/06/2007   S   84 D $ 70.43 99,000 D   Common Stock 03/06/2007   S   1,730 D $ 70.45 97,270 D   Common Stock 03/06/2007   S   100 D $ 70.46 97,170 D   Common Stock 03/06/2007   S   100 D $ 70.47 97,070 D   Common Stock 03/06/2007   S   435 D $ 70.48 96,635 D   Common Stock 03/06/2007   S   1,400 D $ 70.49 95,235 D   Common Stock 03/06/2007   S   35 D $ 70.5 95,200 D   Common Stock 03/06/2007   S   1,220 D $ 70.51 93,980 D   Common Stock 03/06/2007   S   1,200 D $ 70.52 92,780 D   Common Stock 03/06/2007   S   600 D $ 70.53 92,180 D   Common Stock 03/06/2007   S   200 D $ 70.54 91,980 D   Common Stock 03/06/2007   S   1,200 D $ 70.55 90,780 D   Common Stock 03/06/2007   S   2,900 D $ 70.57 87,880 D   Common Stock 03/06/2007   S   2,115 D $ 70.58 85,765 D   Common Stock 03/06/2007   S   600 D $ 70.59 85,165 D   Common Stock 03/06/2007   S   1,820 D $ 70.6 83,345 D   Common Stock 03/06/2007   S   200 D $ 70.61 83,145 D   Common Stock 03/06/2007   S   400 D $ 70.62 82,745 D   Common Stock 03/06/2007   S   500 D $ 70.63 82,245 D   Common Stock 03/06/2007   S   900 D $ 70.64 81,345 D   Common Stock 03/06/2007   S   7,400 D $ 70.65 73,945 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Non-Qualified Stock Option (right to buy)

$ 5.1329

03/06/2007

M

23,600

(1)

01/01/2009

Common Stock

23,600

$ 0

0

D

Non-Qualified Stock Option (right to buy)

$ 6.7657

03/06/2007

M

16,400

(2)

01/02/2010

Common Stock

16,400

$ 0

55,600

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
DENNY JAMES M 333 LAKESIDE DRIVE FOSTER CITY, CA 94404	X

Signatures

/s/ James M. Denny		03/07/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Options vested quarterly over a period of five years beginning January 2, 1999, the date of grant.
(2)	Options vested quarterly over a period of five years beginning January 3, 2000, the date of grant.
Remarks: The exercise and sale transactions reported in this Form 4 are made persuant to a Rule 10b5-1 trading plan established by Mr. Denny on August 17, 2004. The plan has since been amended and restated on August 18, 2005.  These transactions are being reported are being reported on a two-part Form 4 due to space limitations.  This is Part 1 of 2.

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